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• Published Subscription 20 Apr 2019

  Papillary Thyroidcarcinoma in Rats After Administration of Platinum Compounds Daily

  By MS Sastry, S Dighade

  Abstract: Papillary thyroid carcinoma (PTC) predominantly grows in a solid growth pattern with papillary projections, composed of oncocytic cells with “Orphan annie eyes” nuclei. Cisplatin or Cis-Diammine dichloroplatinum (ii) (Cl2H6N2Pt); is a divalent, inorganic and water-soluble first successful platinum containing anticancer drug, used to treat various forms of cancers. The Carboplatin (C6H14N2O4Pt) and Oxaliplatin (C8H14N2O4Pt) are the investigational chemotherapy medicines, belonging to platinum analogue interfere as the Cisplatin with the genetic …

  Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 3, 2015 · pp. 27–31 Read article →