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Comparative Evaluation of Genotoxicity in Peripheral Blood Mononuclear Cells in Oral Precancer and Cancer Patients Using Single Cell Gel ElectrophoresisBy Deep Kumari Yadav, Pooja Senghani, Dhiru Makwana, Rakesh Rawal
Abstract: In the present study the comet assay was performed in peripheral mononuclear cells to evaluate DNA damage among tobacco chewers and smokers. The assay provides a quick, accurate and sensitive way to detect various forms of DNA damage in individual cells. The study comprises 50 oral cancer patients, 12 oral submucous fibrosis patients and 10 healthy controls. The length of the comet tail was used to determine the level of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 26–34 Read article →