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Development and Validation of Simple UV-Spectrophotometric Method of Quantization of Domperidone in Solid Dosage Formulation using Mixed Solvency ConceptBy Sanjay Jain, R. K. Maheshwari, Rajesh Kumar Nema, Indrajeet Singhvi
Abstract: Organic solvents are most frequently employed in spectrophotometric analyses. They may be the sources of pollution. Some of them may be toxic, while others may be costlier. Volatility may be a source of inaccuracy in spectrophotometric estimations. In the present investigation, it was proposed to solubilize Domperidone by the use of mixed solvency concept. Domperidone shows maximum absorbance in the concentrations range of 10–50µg/ml at 287 nm. Method of analyses …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 2, 2017 · pp. 19–23 Read article →