1 publication

• Published Subscription 13 Nov 2023

  Pf Phosphatidylserine decarboxylase: Molecular modeling and inhibithors prediction

  By Mamadou Sangare, Cheickna Cisse, Phillip Cruz, Oudou Diabate, Jeffrey G Shaffer, Jian Li, Seydou Doumbia, Mamadou WELE

  Abstract: Plasmodium falciparum (P.f) is a protozoan parasite responsible for the most severe and deadly form of malaria. The resistance of Pf to last resort antimalarial drugs has been reported, there is an urgent need to identify new therapeutic candidates for drug development. Advancements in bioinformatics technologies provide potential cost and time-effective solutions for predicting therapeutic candidates. Phosphatidylserine decarboxylase (PSD) is a member of the lyase family (more specifically, the carboxy-lyases), …

  Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 · pp. 60–78 Read article →