1 publication

• Published Subscription Article 10 Jan 2023

  Recent Advances in Delivering Strategies of Domperidone Challenges and Opportunities

  By M.A.K. Azad, Md. Masudur Rahman, Shimul Halder, Eva Rahman Kabir

  Abstract: Domperidone (DMP), a potent gastroprokinetic and antiemetic drug, exhibits poor aqueous solubility and limited oral bioavailability. Therefore, to develop oral preparations with optimized oral bioavailability, the pharmacokinetic parameters of DMP need to be controlled. The present review aimed to discuss the physicochemical characteristics of DMP causing its unfavorable oral delivery, to explore the viable oral formulation approaches, and to propose some recent formulation approaches that can mitigate the above mentioned …

  Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 13–24 Read article →