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Up-Regulation of TNF-α by Ethanol Extract of Moringa Oleifera in Benzene-Induced Leukemic Wister Rat: A Possible Mechanism of Anticancer PropertyBy Adebayo Lawrence Adedeji, E.O. Akanni, R. A. Akanni, J. K. Oloke
Abstract: Ethanol extract of Monringa oleifera (EMO) has been shown to possess anti-cancer properties in animal models. The mechanisms of action of its anticancer properties have not been fully demonstrated. We induced leukemia in two groups of seven rats each by intravenous injection of benzene chromasolv solution (0.2 mL) 48 hourly for 4 weeks. EMO (0.2 ml of 100 mg/mL) was administered orally by gavage, after leukemia induction, daily for 4 …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 3, 2014 · pp. 16–21 Read article →