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• Published Subscription 18 Sep 2020

  A REVIEW: P-GLYCOPROTEIN AND ITS ROLE IN CANCER

  By Deekshitha H S, K. Natarajan, Vineeth Chandy

  Abstract: Abstract The review is done on how P-glycoprotein recognizes various substrates and plays a key role in cancer. Chemotherapy is used for cancer treatment but multidrug resistance of cancerous cell is the major obstacle in therapy and also an important aspect which causes failure in the treatment by effluxion of a xenobiotic on the plasma membrane. In humans, P-glycoprotein is important transmembrane transporter. It is located on the apical surface …

  Published in Trends in Drug Delivery · Vol. 7, Issue 2, 2020 · pp. 26–34 Read article →