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    In- silico Design of Novel Inhibitors for Benzimidazole Receptor against Cryptosporidium parvum

    Abstract: Cryptosporidium parvum is an obligate, intracellular, protozoan parasite belonging to the phylum Apicomplexa. Cryptosporidium parvum is increasingly being recognized as an important pathogen causing diarrhea in children, with the highest associated morbidity and mortality, especially among children in developing countries. The highest prevalence of cryptosporidiosis has been documented in children aged 6–12 months. 3D QSAR studies were carried out on benzimidazole derivatives to identify new improved possible inhibitors. kNN-MFA methodology …

    Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 2, 2015 · pp. 1–10 Read article

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